Clinical Study

Association between Micronutrients (Vitamin A, D, Iron) and Schistosome-Specific Cytokine Responses in Zimbabweans Exposed to Schistosoma haematobium

Table 2

𝐹 and 𝑃 values obtained from ANOVA determining the association between cytokine levels and micronutrient levels.

Vit DRBPsTfRFerritinsTfR/ferritin ratioCRP
𝐹 value ( 𝑃 value) 𝐹 value ( 𝑃 value) 𝐹 value ( 𝑃 value) 𝐹 value ( 𝑃 value) 𝐹 value ( 𝑃 value) 𝐹 value ( 𝑃 value)

IFN-γ0.008 (0.931)0.153 (0.701)0.017 (0.898)1.741 (0.206)0.081 (0.779)0.256 (0.616)
IFN-γ* infection status0.047 (0.790)0.806 (0.383)4.631 (0.047)1.312 (0.269)7.516 (0.011)0.009 (0.926)
IL-49.662 (0.004)0.105 (0.751)2.649 (0.123)0.288 (0.599)2.218 (0.140)0.543 (0.467)
IL-4* infection status10.487 (0.003)0.894 (0.358)4.412 (0.052)0.126 (0.727)7.702 (0.010)0.465 (0.500)
IL-50.311 (0.560)0.001 (0.975)0.293 (0.596)1.005 (0.331)0.236 (0.631)1.793 (0.190)
IL-5* infection status0.003 (0.960)0.742 (0.402)0.122 (0.732)10.706 (0.005)0.080 (0.780)0.006 (0.937)
IL-101.509 (0.237)5.786 (0.023)0.001 (0.970)0.875 (0.364)0.042 (0.838)0.520 (0.476)
IL-10* infection status0.372 (0.550)2.831 (0.104)1.336 (0.265)0.237 (0.633)0.038 (0.846)2.243 (0.144)

The effects of the potential confounders sex, age was allowed for first before testing for the effects of the cytokine and the interaction between cytokine and infection status using sequential sums of squares to calculate the 𝐹 value. Significant 𝑃 values are highlighted in bold.