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Journal of Parasitology Research
Volume 2013, Article ID 430413, 6 pages
Research Article

Probiotic Therapy: A Promising Strategy for the Control of Canine Hookworm

1FUNVIC, Faculdade de Pindamonhangaba, Laboratório de Parasitologia, Rodovia Presidente Eurico Gaspar Dutra s/n-Km 99, Pinhão do Una, 12422-970 Pindamonhangaba, SP, Brazil
2Universidade de Taubaté, Campus do Bom Conselho, Laboratório de Parasitologia, Avenida Tiradentes 500, Centro, 12030-180 Taubaté, SP, Brazil
3Universidade de São Paulo, Escola de Engenharia de Lorena, Laboratório de Probióticos Estrada Municipal do Campinho, s/n, 12602-810 Lorena, SP, Brazil

Received 23 July 2013; Revised 22 September 2013; Accepted 26 September 2013

Academic Editor: Bernard Marchand

Copyright © 2013 Matheus Diniz Gonçalves Coêlho et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Canis familiaris is a domestic animal which plays an important role as a pet; however, it is very likely to develop diseases characterized by high morbidity and mortality. In this sense, there are some Ancylostomatidae species that can lead to anemia, weight loss, and abdominal pain. Therefore, the treatment with allopathic drugs is essential for eliminating the parasitism. However, the increasing occurrence of resistance to allopathic treatments stimulates the search for new therapeutic inputs, among which the probiotics stand out and are able to positively alter the intestinal microbiota and exert immunomodulatory effect. Therefore, the present study aimed to evaluate the applicability of using species of Lactobacillus (L. acidophilus ATCC 4536, L. plantarum ATCC 8014, and L. delbrueckii UFV H2B20) to control canine ancylostomiasis. A probiotic preparation containing 1 × 106 CFU of each strain was administered to 10 naturally infected animals, on alternate days for 28 days. It was observed that the treatment with the probiotic preparation led to a significant reduction in EPG of feces (88.83%/ ), as well as an increase in leukocyte and lymphocyte counts, highlighting the potential use of Lactobacillus species in the control of canine ancylostomiasis.