Novel Arsenic Nanoparticles Are More Effective and Less Toxic than As (III) to Inhibit Extracellular and Intracellular Proliferation of Leishmania donovani
Table 1
values for each data point in Figures 2(a) and 2(b).
(a) For As-NPs
Treatment duration (h
% O2 of consumption (mean)a
valuesb
Time (s)
24
5
4.616
0.023
10
6.916
0.023
15
9.340
0.0394
20
8.140
0.0035
25
6.496
0.0015
48
5
2.316
0.023
10
3.253
0.0183
15
3.246
0.0003
20
4.643
0.0004
25
3.726
0.0004
72
5
0.462
0.0001
10
0.456
0.0001
15
0.953
0.0001
20
0.004
0.0001
25
0.425
0.0001
Mean values of percent of O2 consumed by L.d. parasites at every 5 sec up to 25 sec, in presence of 2 M As-NPs for indicated obtained from three independent experiments.
bIt signifies values <0.05.
(b) For As (III)
Treatment duration (h
% O2 of consumption (mean)a
valuesb
Time (s)
24
5
7.356
0.023
10
12.625
0.028
15
16.640
0.0294
20
20.140
0.0135
25
20.496
0.0215
48
5
5.756
0.023
10
12.053
0.0203
15
14.216
0.0013
20
15.603
0.0104
25
15.716
0.0124
72
5
4.062
0.0031
10
8.606
0.0201
15
10.053
0.0101
20
12.614
0.0031
25
14.022
0.0231
Mean values of percent of O2 consumed by L.d. parasites at every 5 sec up to 25 sec, in presence of 20 M As (III) for indicated obtained from three independent experiments.
bIt signifies values <0.05.
