Comparative Study of Modified Quantitative Buffy Coat and Two Rapid Tests in Comparison with Peripheral Blood Smear in Malaria Diagnosis in Mumbai, India
Table 3
Patients infected with P. falciparum .
Modified QBC
PLDH
Parahit total
Sensitivity
98 (94.4–99.5)ab
95.0 (91.3–96.0)*a
70.3 (65.9– 71.2)*b
Specificity
96 (88.7–99.0)cd
98.0 (95.1–99.9)c#
98 (89.2–99.9)#d
Positive predictive value
98 (94.4–99.5)
99.0 (95.1–99.9)
98.6 (92.5–99.9)
Negative predictive value
96 (88.7–99.0)
90.7 (83.7–92.5)
62.0 (56.4–63.2)
Likelihood ratio +
24.5
47.52
35.14
Likelihood ratio −
0.02
0.050
0.30
Odds ratio
1176 (131.09–18730.21)
940.80 (99.17–22239.18)
115.96 (15.96–2389.96)
Relative risk
24.50 (8.35–97.02)
10.68 (5.84–13.31)
2.59 (2.12–2.71)
Kappa
0.94 (0.831–0.985)
0.912 (0.801–0.940)
0.59 (0.48–0.62)
Overall accuracy
0.9733
96.0
0.79
False positive rate
0.04
0.02
0.02
False negative rate
0.02
0.049
0.29
Statistical significant highly significant and #not statistical significant .
aNot statistically significant , bextremely statistically significant. value is less than 0.0001, cnot statistically significant value = 1.0000. dNot statistically significant value = 1.0000.
