Could kDNA-PCR in Peripheral Blood Replace the Examination of Bone Marrow for the Diagnosis of Visceral Leishmaniasis?

Table 2

Sensitivity, specificity, predictive positive value, predictive negative value, probability of false positive, probability of false negative of PB kDNA-PCR and BM kDNA-PCR.

Test	Sensitivity (%)	Specificity (%)	PPV (%)	PNV (%)	PFP (%)	PFN (%)	Efficiency (%) (CI 95%)
PB kDNA-PCR	100	100	100	100	0	0	100 (90.7–100)
BM kDNA-PCR	95.0	100	100	95.2	0	4.8	97.3 (86.2–99.9)

BM kDNA-PCR: kDNA PCR in sample from bone marrow; PB kDNA-PCR: kDNA PCR in sample from peripheral blood; PPV: predictive positive value; PNV: predictive negative value; PFP: probability of false positive; PFN: probability of false negative; CI 95%: 95% confidence intervals.