Research Article

Immune Profile of Honduran Schoolchildren with Intestinal Parasites: The Skewed Response against Geohelminths

Table 2

Geometric means (95%CI) of immunological markers determined in schoolchildren by STH infection status .

ParameterNonparasitizedAscariasisTrichuriasisMix infections
n = 21n = 29

Eosinophils (cells/L)273.5 (240.7–310.8)320.8 (229.7–448.0)410.1 448.9
IgE (IU/mL)722.9 (573.0–912.1)443.9 (159.1–1238.2)726.1 (352.4–1495.9)1463.7
IL-2 (pg/mL)26.1 (21.0–32.4)34.7 (19.7–61.2)24.1 (16.0–36.3)21.3 (14.4–31.6)
IL-4 (pg/mL)1.2 (0.8–1.7)0.7 (0.1–5.4)0.9 (0.1–5.0)0.8 (0.2–2.4)
IL-5 (pg/mL)10.9 (4.6–25.8)17.1 (4.4–66.6)11.8 (9.4–14.9)5.1 (1.2–21.7)
IL-6 (pg/mL)13.7 (11.2–16.8)16.1 (7.9–32.8)10.8 (5.9–19.7)9.8 (6.4–14.8)
IL-8 (pg/mL)107.2 (91.8–125.2)105.8 (65.5–170.9)91.8 (61.1–138.1)99.3 (71.1–138.7)
IL-10 (pg/mL)8.5 (7.1–10.1)15.3 7.1 (4.8–10.5)6.6 (4.9–8.8)
IL-12p70 (pg/mL)9.5 (7.5–12.1)15.3 (5.7–41.1)7.4 (5.2–10.5)6.3 (4.1–9.8)
IL-13 (pg/mL)1.2 (0.9–1.5)4.7 1.3 (0.6–2.7)1.9 (0.9–3.9)
IFN- (pg/mL)131.5 (98.4–175.8)162.9 (49.7–533.2)70.1 95.5 (38.7–235.7)
GM-CSF (pg/mL)55.1 (43.9–69.0)72.8 (38.8–136.5)45.5 (22.1–93.4)45.0 (23.0–87.9)
TNF- (pg/mL)8.2 (6.7–10.2)10.4 (3.7–28.9)9.1 (5.1–16.0)6.4 (3.8–10.7)

STH: soil-transmitted helminth.
One child did not agree on providing blood sample.
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