Inhibitory Activity and Docking Analysis of Antimalarial Agents from Stemona sp. toward Ferredoxin-NADP+ Reductase from Malaria Parasites

Table 1

Inhibition (%) of NADPH-dependent catalytic activity of PfFNR.

Alkaloids	dA/dt	% Inhibition
Control	0.059	-
Croomine	0.039	33.9
Epi-croomine	0.059	0.7
Tuberstemonine	0.052	11.5
Isoprotostemonine	0.088	-48.8
Javastemonine A	0.065	-9.5

Each of alkaloids is 100 ppm; dA/dt is the rate of absorbance change.