Research Article

Comparison of the Accuracy of Four Malaria Diagnostic Methods in a High Transmission Setting in Coastal Cameroon

Table 1

Performance of SD Bioline™ mRDT Pf/Pan test lines with change is parasite density.

S/NParasite density (range)Control Control+ PF line Control + PF+pan lineTotal

1NPS95.37(103/108)4.63 (5/108)0.0 (0/108)108

2≤50010.87 (5/46)84.78 (39/46)4.35 (2/46)46

3501-10000.0 (0/18)44.44 (8/18)55.56 (10/18)18

41001-50000.0 (0/29)41.38 (12/29)58.62 (17/29)29

55001-100000.0 (0/49)16.67 (8/48)83.33 (40/48)48

6>100000.0 (0/34)5.88 (2/34)94.12 (32/34)34

Total 10874101283

Legend. PF: histidine rich protein 2 line (HRP2 line), Pan: parasite specific lactate dehydrogenase line, NPS: No Parasites Seen. Numbers under Control, Control + PF line, and Control + PF + pan line indicate percentages and the numbers in bracket indicate number of observed cases in each parasitaemia range. Samples with mixed infections as well as samples with other forms of malaria were removed from this analysis.