Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 2

Effect of crude methanolic leaf extracts of B. rotundifolia on body weight and PCV of P. berghei infected mice.

Dose mg/kg extract	PCV		Mean PCV	Body weight		Mean BWT
			% change			% change
	Day-0	Day-4		Day-0	Day-4
NC	54.96±1.3	49.78±1.87	-9.55±4.2	24.82±1.22	22.16.98±1.46	-11.03±1.4
200	54.48±0.96	51.32±0.78	-5.83±1.19	27.14±0.51	27.84±1.44	2.71±0.61
350	52.38±2.01	48.76±3.16	-7.4±2.83	27.94±0.41	29.3±6.9	4.38±0.87
500	53.9±2.81	50.96±2.82	-5.51±0.96	28.84±0.72	30.18±0.51	4.62±0.42
QC	54.96±0.84	56.62±0.57	4.51±1.71	31.4±0.68	33.5±2.5	6.79±1.3

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key= values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; NC= negative control (0.2ml of dH2O).