Research Article

Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 3

Effect of crude chloroform leaf extracts of Balanites rotundifolia on body weight and PCV of P. berghei infected mice.

Dose mg/kg extractPCVMean PCVBody weightMean BWT
% change% change
Day-0Day-4Day-0Day-4

NC64.86±0.6549.98±2.34-22.78±4.324.8±0.9622.6.±1.07-8.67±3.6
20062.18±0.9648.18±3.38-22.14±5.5427.2±0.5826±0.37-4.41±2.3
35060.02±1.152.82±2.51- 7.68±5.6727 ±0.4426±0.58-3.47±0.87
50062.62±1.0554.5±1.41-12.82±3.0425±0.7124.8±1.39-0.8±1.08
QC64.91±0.6461.74±0.59-4.81±0.6326.6±1.3626.4±0.8-1.5±0.8

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key= values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; NC= negative control (0.2ml of dH2O); BWT=body weight.