Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 4

Effect of crude methanolic root extracts of S. persica on body weight and PCV of P. berghei infected mice.

Dose mg/kg extract	PCV		Mean PCV	Body weight		Mean BWT
	% change					% change
	Day-0	Day-4		Day-0	Day-4
NC	55.05±1	45.01±2.06	-18.03±9.9	29.46±0.66	27.58±0.43	-6.39±0.79
200	54.57±1.31	52.25±1.16	-3.76±0.75	24.62±1.36	25.84±1.36	4.91±1.19
350	54.68±0.94	52.25±1.03	-4.76±0.67	28.88±0.28	29.72±0.45	2.9±0.1
500	54.25±0.8	51.72±0.94	-4.67±0.73	25.4±0.70	25.9±1	3.81±1.7
QC	54.85±0.38	58.06±0.83	4.58±0.61	28.18±1	31.02±0.74	10.31±2.3

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key= values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; NC= negative control (0.2ml of dH2O); BWT=body weight.