Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 5

Effect of crude chloroform leaf extracts of S. persica on body weight and PCV of P. berghei infected mice.

Dose mg/kg extract	PCV		Mean PCV	Body weight		Mean BWT
			% change			% change
	Day-0	Day-4		Day-0	Day-4
NC	64.86±0.65	49.98±2.34	-22.78±4.3	24.8±0.96	22.6.±1.07	-8.67±3.6
200	60.92±0.97	52.54±2.06	-13.84±2.44	25.6±0.58	23.3±0.66	-8.53±3.27
350	61.36±1.35	54.56±0.97	-10.93±2.28	26.2 ±0.86	25.2±0.66	-3.72±1.09
500	61.74±0.72	48.62±1.62	-19.62±2.51	25.8±0.66	23.4±0.51	-9.11±2.68
QC	64.88±0.64	61.74±0.26	-4.81±0.63	26.6±1.36	27.4±0.8	3.11±0.8

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key= values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; NC= negative control (0.2ml of dH2O); BWT=body weight.