Phytochemical Screening and In Vivo Antimalarial Activity of Two Traditionally Used Medicinal Plants of Afar Region, Ethiopia, against Plasmodium berghei in Swiss Albino Mice

Table 6

Effect of B. rotundifolia on percentage parasitemia, and survival time of P. berghei infected mice in the 4-day suppressive test.

Dose mg/kg extract	% Parasitaemia ± SEM	% Suppression	MST
NC	77.22±2.11	0.00	6±0.63
200	45.29±1.42	41.33±1.1	9±0.83
350	40.08±2.81	48.1±1.4	10.2±0.2
500	30.44±0.89	60.59±3.25	16.4±0.51
QC	0.00	100	30(+)

Means in a column followed by the same letter do not differ significantly (P>0.05).
Key: values are presented as M±SEM; n=5; CQ= Chloroquine Phosphate; NC = negative control (0.2ml of dH2O); + = maximum days of followup; MST=mean survival time.