Research Article

A New Method to Test Molluscicides against the Philippine Schistosomiasis Snail Vectors

Table 5

Lethal dose ratios with their 95% confidence limits for niclosamide and tagpo extract using conventional (cpt) and miniaturized (mpt) plate tests against Oncomelania hupensis quadrasi snails.

Lethal ratioNiclosamideTagpo extract
LC50LC90LC50LC90

cpt/mpt 10.820 (0.663, 0.977)0.991 (0.632, 1.351)0.948 (0.848, 1.048)0.997 (0.818, 1.177)
mpt 1/mpt 20.939 (0.793, 1.084)1.101 (0.787, 1.416)0.932 (0.833, 1.031)0.877 (0.707, 1.048)
mpt 1/mpt 30.916 (0.774, 1.057)1.068 (0.758, 1.377)0.861 (0.782, 0.939)0.931 (0.787, 1.074)
mpt 1/mpt 40.912 (0.769, 1.056)1.026 (0.719, 1.333)0.932 (0.833, 1.031)0.877 (0.707, 1.048)
mpt 2/mpt 30.976 (0.841, 1.110)0.969 (0.729, 1.209)0.923 (0.837, 1.010)1.061 (0.867, 1.254)
mpt 2/mpt 40.972 (0.835, 1.109)0.931 (0.690, 1.172)1.000 (0.892, 1.108)1.000 (0.783, 1.217)
mpt 3/mpt 40.996 (0.857, 1.136)0.961 (0.708, 1.213)1.083 (0.982, 1.184)0.943 (0.771, 1.115)

Difference is interpreted as significant.