The Chronology of Angiostrongylus vasorum (Baillet, 1866), Kamensky, 1905: Infection in Biomphalaria glabrata (Say, 1818)

Figure 3

Histological sections of Biomphalaria glabrata infected with 1000 L1 of A. vasorum. Hematoxylin and eosin staining. (a) Granuloma formation of two distinct layers, an internal with cells of epithelioid aspect (black asterisk) and outer, with cells like fibroblast (arrow). The white cross shows the formation of the cell button on the one side of the larva after six days of the beginning of infection; (b) detail of the larva (arrow) within the albumen gland being surrounded by a cell reaction; the white asterisk shows the cell reaction present six days after the beginning of infection; (c) granuloma formation within the renal artery (white asterisk) fourteen days after the beginning of infection. Renal space is represented by the black asterisk, and the larva indicated by the arrow is an L2 because this has granules around the intestine (14 days); (d) granuloma in the dorsalis pedis region determining a thinning of the epithelium (arrow) fourteen days after the beginning of infection; (e) larva in the foot fibromuscular tissue with a strong reaction in the form of button (black asterisk) without typical presentation of granuloma around, after twenty days of the beginning of infection; (f) larva (white arrow) in a less typical granuloma located in the conjunctive tissue around the kidney (black asterisk) thirty days after the beginning of infection. (g) Weak cellular reaction around the larva with looser appearance. It can be observed larvae within mucus cells (black asterisk) thirty days from the beginning of infection; (h) larvae located in foot fibromuscular tissue without presenting typical granulomatous response, keeping the space even more clear after thirty days at the beginning of infection. Magnifications: (a–h) 35 μm.

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