Therapeutic Efficacy of Artemether-Lumefantrine (Coartem®) for the Treatment of Uncomplicated Falciparum Malaria in Africa: A Systematic Review

Table 2

Baseline characteristics of the study subjects with uncomplicated falciparum malaria in Africa, 2015-2019.

Author, year	Mean age in yrs	Mean wt in kg	Mean T in ^0C	Mean Hgb in g/dl	GMPD	Presence of gametocytes (%)
Mwaiswel, 2016	10	34.3	38.3	—	8384	—
Koita, 2017	31.9	67.5	—	12.5	12000	—
Yeka, 2016	2.8	—	37.5	10.2	21616	13.9
Ndounga, 2015	5.4	19.6	—	10.5	30700	—
Ebstie, 2015	-NR	40.3	38.7	10.8	—	3
Sirima, 2016	2.5	—	38·7	9.5	65299.4	5
Chandra, 2015	2.7	12.8	—	—	—	—
Kilonzi, 2019	2.6	—	38.5	9.3	8745.8	—
Sondo, 2015	3.26	11	38.4	9	30529	—
Salvador, 2017	3.1	—	38.0	9.2	30 115	—
Davlantes, 2018	3	12	—	10.1	22340	—
Kakolwa, 2018	—	—	38.1	—	24400	—
Plucinski, 2015	—	—	—	—	—	—
Denoeud,2016	1.9	8.7	—	8.7	11200	—
Mekonnen, 2015	17.3	34.4	38.8	11.6	8404	2.2
Plucinski, 2017	6.4	18	—	10.2	20151	—
Smith, 2018	3.4	—	38.1	—	14 272	—
Ebenebe, 2018	3.3	13.4	37.9	10.1	16337	3.1
Warsame, 2017	12.3	—	38	—	9714	—
Grandesso,2018	2.5	10.5	38.9	9.7	46506	4.2
Adeel, 2016	—	—	38.2	—	11203	—
Niaré, 2016	9	22.7	—	10.9	—	—
Paczkowski, 2016	2.6	11.3	≥37.5	9.8	35512	—
De Wit, 2016	2.6	—	39.0	9.7	45154	—
Dambe, 2015	2.6	11.4	38.5	—	33080	2.1
Wudneh, 2016	13	41.5	37.9	13.7	13441.6	4.4
Roth, 2018	6.4	22.4	37.3	11.9	23672.5	4.17
Nji, 2015	4.8	17.8	38	9.9	14808	—
Ukah, 2015	29.4	—	—	—	12484	—
Dama, 2018	—	—	—	—	24325	—
Sowunmi, 2017	5	—	38.1	11.8	27 791	6
Sowunmi, 2016	4.5	—	38.1	9.8	24151.5	—
Nega, 2016	18.4	40.9	38.2	12.4	11509.6	5.5
Teklemariam, 2017	15.1	39.6	38.5	13.2	27798	7.6
Ogouyèm2016	2.6	—	38.7	8.9	42329	—
Getnet, 2015	19.4	35	38.3	12.3	7,898	10
Ayogu, 2015	—	—	—	—	49225	—
Abuaku, 2016	—	—	38.1	10.2	39,983	3.3
Dorkenoo, 2016	3	—	38.8	10	30498	4.5

yrs: years; wt: weight; kg: kilogram; ⁰C: degree Celsius; T: temperature; Hgb: hemoglobin; GMPD: Geometric mean parasite density per microliter of blood; nr: not reported.