Therapeutic Efficacy of Artemether-Lumefantrine (Coartem®) for the Treatment of Uncomplicated Falciparum Malaria in Africa: A Systematic Review

Table 3

Summary of treatment outcomes of uncomplicated malaria treatment using AL in Africa, 2015-2019.

Treatment outcome
Cure rate	ACPR PCRu	87% (95% CI: 85-90%)
	ACPR PCRc	97.0% (95% CI: 96-98%)
Treatment failure	ETF, %	0-2.5%
	LCF n, %	0-25.6%
	LPF n, %	0-52.6%

ACPR: adequate clinical and parasitological response; PCRu: polymerase chain reaction uncorrected; PCRc: PCR corrected; ETF: early treatment failure; LCF: late clinical failure; LFU: lost follow-up; LPF: late parasitological; n: final number; %: percent.