The Effectiveness of Varying Combination Ratios of A. cordifolia and M. indica against Field and Laboratory Strains of P. falciparum In Vitro

Table 2

The Compusyn drug combination estimated dose of A. cordifolia with M. indica on the three parasite strains.

	HE/combo	CI value	Dose Ac	Dose Mi
NF54	Ac		19.67
	Mi			98.98
	A2 : M1	0.75	13.38	6.69
	A1 : M1	0.78	12.81	12.81
	A10 : M1	2.56	49.41	4.94
FA8	Ac		13.73
	Mi			27.62
	A2 : M1	3.3488	3.6819	1.8409
	A1 : M2	3.03	20.85	41.71
	A1 : M1	2.41	22.14	22.14
CamWT	Ac		150.65
	Mi			169.48
	A1 : M2	0.19	10.42	20.84
	A1 : M1	0.32	25.44	25.44
	A10 : M1	1.05	145.40	14.54

, <1, and >1 depict additive effect, synergism, and antagonism, respectively. Ac: A. cordifolia; Mi: M. indica extract; CamWT: CamWT_580Y; syn: synergy; add: additive; anta: antagonistic.