Activity of Combinations of Antioxidants and Anthelmintic Drugs against the Adult Stage of Schistosoma mansoni

Figure 1

Structures of anthelminthic drugs, anticancer drugs, and antioxidant biomolecules evaluated either alone or combined against S. mansoni adult worms. The anthelmintic drugs are depicted in blue, anticancer drugs in red, and antioxidant biomolecules in green. PZQ: praziquantel; FBZ: flubendazole; AS: artesunate; DiPept: L-Tyr-L-Ser; Resv: resveratrol; Mel: melatonin; Flav: flavone; NAC: N-acetyl-L-cysteine; Curc: curcumin; OXA: 4-phenyl-1,2,5-oxadiazole-3-carbonile-2-oxide.