Journal of Parasitology Research

Research Article

Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya

Table 2

values of the of the selected plant extracts assayed against CQ-sensitive (D6) and CQ-resistant (W2) strains of P. falciparum.


Plant (parts used)		IC₅₀(μg/ml)
Plant (parts used)	Solvent of extraction	D6	W2

Terminalia brownii Fresen. (leaf)	H₂O
	MEOH
	DCM
Erythrina abyssinica Lam. Ex DC. (stem bark)	H₂O
	MEOH
	DCM
Schkuhria pinnata (lam.) Kuntze (whole plant)	H₂O
	MEOH
	DCM
Zanthoxylum chalybeum Engl. (leaf)	H₂O
	MEOH
	DCM
Leonotis mollissima Gurke. (leaf)	H₂O
	MEOH
	DCM
Tithonia diversifolia (Hemsl.) A. Gray (fruit)	H₂O
	MEOH
	DCM
Tithonia diversifolia (Hemsl.) A. Gray (leaf)	H₂O
	MEOH
	DCM
Senna didymobotrya (Fresen.) Irwin & Barneby (pod)	H₂O
	MEOH
	DCM
Senna didymobotrya (Fresen.) Irwin & Barneby (leaf)	H₂O
	MEOH
	DCM
Carissa edulis (Forssk.) Vahl (leaf)	H₂O
	MEOH
	DCM
Sterculia africana (Lour.) Fiori (stem bark)	H₂O
	MEOH
	DCM

Values are presented as ; ^a5 MEOH (D6) vs. H₂O (D6), ^b DCM (D6) vs. H₂O (D6), ^c DCM (D6) vs. MEOH (D6), ^d MEOH (W2) vs. H₂O (W2), ^e DCM (W2) vs. H₂O (W2), ^f DCM (W2) vs. MEOH (W2), ^g H₂O (D6) vs. H₂O (W2), and ^h MEOH (D6) vs. MEOH (W2) by one-way ANOVA with Tukey’s post hoc test. DCM: dichloromethane; MEOH: methanol; H₂O: water.