Research Article

Antiplasmodial and Cytotoxic Activities of Extracts of Selected Medicinal Plants Used to Treat Malaria in Embu County, Kenya

Table 3

Mean parasitemia, suppression, and survival time of mice in days (±SD) for extracts at 100 mg/kg.

Plant (parts used)Solvent of extraction usedMean parasitemia% suppressionMean survival time in days

Terminalia brownii Fresen (leaf)H2O
MEOH
DCM
Erythrina abyssinica Lam. Ex DC (stem bark)H2O
MEOH
DCM
Schkuhria pinnata (Lam.) Kuntze (whole plant)H2O
MEOH
DCM
Zanthoxylum chalybeum Engl. (leaf)H2O
MEOH
DCM
Leonotis mollissima Gurke (leaf)H2O
MEOH
DCM
Tithonia diversifolia (Hemsl.) A. Gray (fruit)H2O
MEOH
DCM
Tithonia diversifolia (Hemsl.) A. Gray (leaf)H2O
MEOH
DCM
Senna didymobotrya (Fresen.) Irwin & Barneby (pod)H2O
MEOH
DCM
Senna didymobotrya (Fresen.) Irwin & Barneby (leaf)H2O
MEOH
DCM
Carissa edulis (Forssk.) Vahl (leaf)H2O
MEOH
DCM
Sterculia africana (Lour.) Fiori (stem bark)H2O
MEOH
DCM

a between the treated and control groups for survival times. b between water and methanol extracts. c between water and DCM. d between methanol and dichloromethane. L: leaves; SB: stem bark; WP: whole plant; F: fruit; P: pods.