Research Article

In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae)

Table 3

Effect of Faurea speciosa extract on body weight and rectal temperature of P. berghei-infected mice in the suppressive test.

TreatmentDose (mg/kg)Average body weight (g)Average rectal temperature (°C)
Day 0Day 3Day 0Day 3

Saline021.5021.20-1.4237.8337.40-0.43
Extracts10019.0019.804.2138.0037.47-0.53
20019.7020.705.0838.0737.83-0.23
40027.5027.801.0938.1737.97-0.20
Artesunate1024.9025.904.0238.1338.130.00

: difference in body weight between day 0 and day 3 expressed as a percentage; : difference in rectal temperature between day 0 and day 3.