Research Article

In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae)

Table 5

Effect of Faurea speciosa extract on body weight and rectal temperature of P. berghei-infected mice in the curative test.

TreatmentDose (mg/kg)Body weight (g)Temperature (°C)
Day 3Day 7Day 3Day 7

Saline026.6325.87-2.8837.6337.800.17
Extracts10027.8329.204.9137.3037.20-0.10
20024.2024.531.3837.737.37-0.33
40022.6322.871.0337.8337.60-0.23
Artesunate1023.5023.871.5638.1337.93-0.20

: difference in body weight between day 0 and day 3 expressed as a percentage; : difference in rectal temperature between day 0 and day 3.