Research Article

In Vivo Antiplasmodial Activity and Toxicological Analyses of the Ethanolic Leaf and Twig Extract of Faurea speciosa Welw. (Proteaceae)

Table 7

Effect of Faurea speciosa extract on body weight and rectal temperature of P. berghei-infected mice in the prophylactic test.

TreatmentDose (mg/kg)Average body weight (g)Average rectal temperature (°C)
Day 3Day 7Day 3Day 7

Saline025.3723.63-6.8337.7037.47-0.23
Extracts10027.4727.13-1.2138.4338.20-0.23
20026.9327.000.2538.1338.300.17
40025.7725.970.7837.8038.130.33
Mefloquine1027.6327.670.4838.2338.03-0.20

: difference in body weight between day 0 and day 3 expressed as a percentage; : difference in rectal temperature between day 0 and day 3.