Anemia, Thrombocytopenia, and Changes in Biochemical Parameters Occurring in Patients with Uncomplicated Plasmodium falciparum Malaria: Data Analysis from Antimalarial Efficacy-Randomized Trials in Dakar and Kaolack Regions, Senegal

Table 5

Biochemical parameter changes from day 0 to day 7 by treatment arms.

Treatment group	Point estimate changes of biological parameters from day 0 to day 7 (95% CI)	value	Mean difference (95% CI)	value
AST (IU/l)
ASAQ		<10^-3		<10^-3
AL		<10^-3		<10^-3
DHAPQ		0.003		0.79
ASMQ		<10^-3		0.29
				0.07
				0.6
ALT (IU/l)
ASAQ		<10^-3		1
AL		<10^-3		0.02
DHAPQ		0.15		1
ASMQ		<10^-3		1
				0.04
				0.01
Creatinine (6-14 mg/l)
ASAQ		<10^-3		1
AL		0.1		<10^-3
DHAPQ	-0.08 (-0.3–0.13)	0.45		<10^-3
ASMQ		0.33		<10^-3
				<10^-3
				<10^-3
Bilirubin (0.23-1 mg/dl)
ASAQ	0.35 (0.17–0.52)	0.0001		<10^-3
AL	0.31 (0.2–0.43)	<10^-3		<10^-3
DHAPQ		<10^-3		<10^-3
ASMQ	0.41 (0.29–0.54)	<10^-3		<10^-3
				<10^-3
				<10^-3