Macrofilaricidal Activity, Acute and Biochemical Effects of Three Lichen Species Found on Mount Cameroon

Table 2

Cytotoxicity and selectivity indices of lichen extracts.

Extract code	CC50 (μg/mL)	IC50 (μg/mL)			IC100 (μg/mL)			Selectivity index (CC50/IC50)
	Cells	AM	AF	MF	AM	AF	MF	AM	AF	MF
USahex	122.8	32.01	36.34	ND	62.5	125	ND	3.84	3.38	ND
USamet	126.8	32.61	41.26	101.8	62.5	125	125	3.89	3.07	1.25
Pamhex	85.59	52.43	64.42	ND	15.625	250	ND	1.63	1.33	ND
Pammet	171.9	8.059	77.64	ND	15.625	250	ND	21.33	2.21	ND
Hethex	23.97	14.48	72.74	ND	31.25	250	ND	1.66	0.33	ND
Hetmet	37.46	34.65	115.2	ND	125	250	ND	1.08	0.33	ND

Extract codes are defined in Table 1. MF = microfilariae; AM = adult male; AF = adult female; ND = not done.