Effectiveness of Polyclonal Antibody Immunoconjugate Treatment with Propamidine Isethionate for Amoebic Keratitis in Golden Hamsters

Figure 5

Immunofluorescence for IL-1β, IL-10, and caspase 3. No significant differences were found between the healthy and sham groups. Inoculation of the amoeba causes up-regulation of IL-1β, IL-10, and caspase 3. Administration of propamidine isethionate causes significant down-regulation of IL-1β, IL-10, and activated caspase 3. Immunoconjugate administration significantly reduces cytokine expression. Statistical test was performed according to the normality test, applying ANOVA and Tukey post-hoc test. *; **; and ***.