Journal of Probability and Statistics / 2012 / Article / Fig 1

Research Article

The Transmission Disequilibrium/Heterogeneity Test with Parental-Genotype Reconstruction for Refined Genetic Mapping of Complex Diseases

Figure 1

Power of RC-TDH (solid) and RC-TDT (dashed) in Table 5 (scenario 1). This figure is based on scenario 1: , , , and . The type I error rate is 0.001 based on 500 independent replicates of 200 nuclear families, 50% of which without parental information. Every family contains 3 sibs and at least one is affected. is the measurement for linkage disequilibrium as defined by in Section 4.1. When  = 0, there is no linkage disequilibrium.
256574.fig.001

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.