Research Article

A Two-Stage Penalized Logistic Regression Approach to Case-Control Genome-Wide Association Studies

Table 3

The simulated average PDR and FDR under Model 2: multiplicative effects within loci but not between loci.

( 𝑛 , 𝑃 ) 𝜆 𝑞 PDRFDR
TPLR MT TPLR MT

(800,1000)  0.50.1 0.2650.175 0.0860.352
0.50.2 0.6500.550 0.0710.763
0.70.1 0.7900.710 0.0480.758
0.70.2 0.9501.000 0.0500.954

(800,5000) 0.50.1 0.1750.085 0.0790.595
0.50.2 0.6100.405 0.0770.928
0.70.10.7200.4800.0620.776
0.70.20.9400.9300.0510.980