Clustering-Based Method for Developing a Genomic Copy Number Alteration Signature for Predicting the Metastatic Potential of Prostate Cancer
Plot of ranked proximity score for MSK signature 2. Proximity represents the number of times a particular sample clustered with the MSK metastasis profile 2. The samples with higher scores (red points) are classified as inferred mPTs and the samples with lower scores (blue points) are classified as inferred iPTs. Primary tumors (hollow points) interspersed with the blue iPT tumors were excluded as iPTs for MSK signature 2 because they did not consistently classify as iPTs in the proximity analysis using MSK signature 1.
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