Clustering-Based Method for Developing a Genomic Copy Number Alteration Signature for Predicting the Metastatic Potential of Prostate Cancer

Figure 9

Boxplot showing the metastatic potential scores for all samples involved in the analysis. All high-risk tumors are shown in the left three boxes (metastases, progressors, and lymph-node-positive samples), while unknown control primary tumors and the publically available cell line data are shown in the right boxes. The red "+" symbols in the lymph-node-positive box represent those samples from the MSK dataset, distinguishing them from the SU cohort lymph-node-positive samples. The green "x" symbols in the control primary tumors plot represent selected low-risk primary tumors (individuals with no biochemical recurrence (PSA) for at least 80 months).