935621.fig.001
Figure 1: Sample size versus l o g 𝑀 (base 10) to detect effect sizes Δ = 0 . 5 , 1 or 2 with 1 𝛽 = 9 0 % power at the familywise significance level 𝛼 = 5 % , when Bonferroni adjustment is used. The open circles represent the sample sizes calculated based on exact normal quantiles (2.2).