Research Article
Berberine Reshapes the Balance of the Local Renin-Angiotensin System by Modulating Autophagy under Metabolic Stress in Pancreatic Islets
Figure 4
Autophagy mediated the protective effect of berberine in pancreatic islet cells. (a) Representative images of the islet cell structure by TEM. The black arrows show autophagosomes. (b, c) Representative images of the islet cell structure by immunohistochemistry (×400). WT (): wild-type C57BL/6 J mice; ACE2KO (): ACE2KO mice. The arrows show autophagy.