Aldosterone Induces the Proliferation of Renal Tubular Epithelial Cells In Vivo but Not In Vitro

Figure 6

Synergistic effect of aldosterone and salt on proliferation of mDCT cells. mDCT cells were in a medium containing 161 mmol/L Na⁺. Cells were stimulated by different concentrations of aldosterone. Cell counting and flow cytometry were used to detect changes in the cell number and DNA content. (a) Change in DNA content after 12 h of stimulation and (b) change after 24 h of stimulation in mDCT cells. The result was presented in (c); values were given as the . (d) The cell counts of mDCT after were stimulated for 12 hours. (e) The cell counts of mDCT after were stimulated for 24 hours.

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