Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer

<div>Current understanding of the renin-angiotensin system 2021. Black font indicates the classical RAS circa 1990. Red font indicates additional metabolic and signaling pathways that have been incorporated into the RAS since 1990. Proteins, enzymes, and receptors indicated in gray boxes are the proteins whose genes were evaluated in this analysis. Dotted lines indicate hypothetical pathways. <svg height="11.97pt" id="M1" style="vertical-align:-0.04979992pt" version="1.1" viewbox="-0.0498162 -11.9202 7.7589 11.97" width="7.7589pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M229 220C199 245 182 267 182 298C182 346 262 389 295 416C330 444 345 469 345 505C345 588 267 665 181 665H180C163 665 116 654 84 626C70 614 63 603 63 589C63 564 91 544 106 544C118 544 157 598 223 598C259 598 281 579 281 544C281 504 220 464 182 437C118 389 96 359 96 324C96 262 170 207 208 194L229 220ZM192 -12C226 -12 251 12 251 49C251 83 226 109 193 109S135 83 135 49C135 12 160 -12 192 -12Z"></path></g><g transform="matrix(.0091,0,0,-0.0091,3.567,-5.741)"><path d="M229 220C199 245 182 267 182 298C182 346 262 389 295 416C330 444 345 469 345 505C345 588 267 665 181 665H180C163 665 116 654 84 626C70 614 63 603 63 589C63 564 91 544 106 544C118 544 157 598 223 598C259 598 281 579 281 544C281 504 220 464 182 437C118 389 96 359 96 324C96 262 170 207 208 194L229 220ZM192 -12C226 -12 251 12 251 49C251 83 226 109 193 109S135 83 135 49C135 12 160 -12 192 -12Z"></path></g></svg>Uncharacterized enzymatic mediators.</div>

Journal of the Renin-Angiotensin-Aldosterone System

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Figure 1

Figure 1: Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer 