|
Antagonist MasR (A779) |
Model | Effect |
Male | Female | Ref |
|
Water loaded male Wistar rats | ⬆Urine volume | — | [70] |
Virgin female | — | ⬆Urine volume | [72] |
Pregnant female | — | ⬇Urine volume | [72] |
Male and female SHRs+Ang II infusion | ⬆Blood pressure (there was no sex difference) | ⬆Blood pressure (there was no sex difference) | [54] |
Male and female Wistar rats+Ang 1-7 infusion | ⬇RBF response to Ang 1-7 (the decrease was not significant) | ⬇RBF response to Ang 1-7 | [88] |
Male Wistar rats | ⬇RBF | — | [89] |
OVX female Wistar rats+ERT | — | ⬆RBF response to Ang 1-7 infusion (this response increased significantly in nonestradiol treated compared to the estradiol-treated rats) | [90] |
Male and female Wistar rats+block of AT1R+AT2R | ⬆RBF response to Ang 1-7 infusion | This response did not occur in female animals | [91, 92] |
Male and female Wistar rats+block of AT1R+AT2R | RBF response did not any change between males and females | RBF response did not any change between males and females | [93] |
OVX female Wistar rats+BK agonist | — | ⬆RBF response to Ang 1-7 infusion (in OVX group was greater than OVX+ERT group insignificantly) | [95] |
OVX female Wistar rats+B2R antagonist+ERT | — | ⬆RBF response to Ang 1-7 infusion (when B2R alone blocking, the role of estradiol was highlighted) | [96] |
Male and female Wistar rats+PD123319 | ⬇RBF response to Ang II infusion | Attenuated ⬇ RBF response to Ang II infusion in females but not male | [97] |
Male and female Wistar rats+2K1C | ⬆RBF responses to Ang II infusion (no difference between the sexes) | ⬆RBF responses to Ang II infusion (no difference between the sexes) | [98] |
Male and female Wistar rats+2K1C+AT1R block | ⬇RBF responses to Ang II infusion (this response in males significantly more than in females) | ⬇RBF responses to Ang II infusion | [98] |
OVX female Wistar rats+ERT | — | ⬇RBF response to Ang II infusion (the reduction was significant compared to other groups) | [99] |
Female Wistar rats+2K1C+ERT | — | ⬇RBF response to Ang II infusion (there was no difference between groups) | [99] |
Male Wistar rats+2K1C+IPC+I/R | ⬆RBF response to Ang II infusion (significant difference with sham group) | — | [100] |
Male Wistar rats+2K1C+I/R | ⬆RBF response to Ang II infusion (significant difference with sham group) | — | [100] |
Male and female Wistar rats+moderate I/R | ⬆RBF response to Ang II infusion (was not significant compared to the vehicle group) | ⬆RBF response to Ang II infusion (was significant compared to the vehicle group) | [101] |
Male and female Wistar rats+moderate I/R+PD123319 | ⬆RBF response to Ang II infusion (was not significant compared to the vehicle group) | ⬆RBF response to Ang II infusion (was significant compared to the vehicle group) | [101] |
Male Wistar rats | ⬇RBF response to Ang 1-7 infusion | — | [104] |
Male Wistar rats+UUO | ⬇RBF response to Ang 1-7 infusion | — | [104] |
Male Wistar rats+RUUO | ⬇RBF response to Ang 1-7 infusion | — | [104] |
Male Wistar rats+normal-sodium diet | Increase GFR, had no significant effect on MAP, UF, UNaV, or FENa | — | [105] |
Male Wistar rats+low-sodium diet | No effect on GFR, had no significant effect on MAP, UF, UNaV, or FENa | — | [105] |
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