Tolvaptan Improves Contrast-Induced Acute Kidney Injury

Figure 3

Effect of toraveptan on apoptosis in renal tubular cells caused by contrast-induced acute kidney injury. (a) TUNEL staining of rat kidney tissues to detect tubular cell apoptosis. (b) Western blot of rat kidney tissues to detect c-caspase 3, BAX, and Bcl-2 protein expression; CIN: contrast-induced nephropathy; TOL: tolvaptan; ML385: Nrf2 inhibitor. per group. Data are presented as . , , and vs. control group; ^# and ^## vs. CIN group; & and && vs. CIN + TOL group.

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