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Journal of Sensors
Volume 2009, Article ID 215085, 11 pages
Review Article

Nanostructure-Enhanced Surface Acoustic Waves Biosensor and Its Computational Modeling

1Department of Bioengineering, Clemson University, Clemson, SC 29634, USA
2Department of Electrical and Computer Engineering, Clemson University, Clemson, SC 29634, USA
3Institute for Biological Interfaces of Engineering, Clemson University, Clemson, SC 29634, USA

Received 29 December 2008; Revised 1 May 2009; Accepted 23 June 2009

Academic Editor: Wojtek Wlodarski

Copyright © 2009 Guigen Zhang. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Surface acoustic wave (SAW) devices are considered to be very promising in providing a high-performance sensing platform with wireless and remote operational capabilities. In this review, the basic principles of SAW devices and Love-mode SAW-based biosensors are discussed first to illustrate the need for surface enhancement for the active area of a SAW sensor. Then some of the recent efforts made to incorporate nanostructures into SAW sensors are summarized. After that, a computational approach to elucidate the underlying mechanism for the operations of a Love-mode SAW biosensor with nanostructured active surface is discussed. Finally, a modeling example for a Love-mode SAW sensor with skyscraper nanopillars added to in its active surface along with some selected results is presented.