Sensitivity Improvement of an Impedimetric Immunosensor Using Functionalized Iron Oxide Nanoparticles

Table 5

Comparison of analytical parameters of immunosensors based on SAM and immunosensor based on iron oxide nanoparticles.

	Analytical parameters	SAM system	IrNp System
Optical characterization	detection limit	4.5 𝜇g/ml	300 ng/ml
	sensitivity	0.003^∘⋅𝜇g^−1⋅ml	0.094^∘⋅𝜇g^−1⋅ml
	Dynamic range	4.5 to 15 𝜇g/ml	0.3 to 1 𝜇g/ml
	The time response	45 minutes	30 minutes
	reproducibility	6.3%	5.7%
Electrical characterization	detection limit	1 ng ml^−1	500 pg ml^−1
	sensitivity	257.3Ω⋅cm^2⋅𝜇g^−1⋅ml	1871Ω⋅cm^2⋅𝜇g^−1⋅ml
	Dynamic range	1 to 50 ng ml^−1	0.5 to 50 ng ml^−1
	The time response	45 minutes	20 minutes
	reproducibility	8.7%	7.5%