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Journal of Sensors
Volume 2016 (2016), Article ID 1830843, 7 pages
http://dx.doi.org/10.1155/2016/1830843
Research Article

Rapid and Accurate Identification of Adulterants via an Electronic Nose and DNA Identification Platform: Identification of Fake Velvet Antlers as an Example

School of Chinese Materia Medica, Beijing University of Chinese Medicine, No. 6, Wang Jing Zhong Huan South Street, Chaoyang District, Beijing 100102, China

Received 19 June 2015; Revised 26 October 2015; Accepted 27 October 2015

Academic Editor: Kourosh Kalantar-Zadeh

Copyright © 2016 Guojie Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Adulterants in Chinese medicines had always affected the efficacy of Chinese medicines and resulted in safety problems in drug use. We aimed to take the identification of fake velvet antlers as an example for establishment of a rapid and accurate identification platform for modern pharmaceutical companies and markets of Chinese medicine. Methods. In this study, we developed a novel electronic nose and DNA identification platform for identifying fake velvet antlers. Electronic nose was designed for rapid screening, while accurate identification based on DNA method was performed when electronic nose fails to accurately identify some complex samples. Results. Rapid identification of different velvet antlers based on electronic nose showed the good identification power, while accurate identification based on DNA sequencing technology demonstrated a correct identification rate of 100%. We also mined thirty conserved specific sites of fake velvet antlers, which was useful for further work. Conclusions. The results suggested that electronic nose and DNA identification platform was effective for rapid and accurate identification of fake velvet antlers. It highly improved efficiency and decreased cost of identification and could provide a new sight and inspiration for identification in the field of traditional Chinese medicine (TCM).