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Journal of Sensors
Volume 2017, Article ID 3719853, 7 pages
https://doi.org/10.1155/2017/3719853
Research Article

Modeling of a Piezoelectric MEMS Micropump Dedicated to Insulin Delivery and Experimental Validation Using Integrated Pressure Sensors: Application to Partial Occlusion Management

Debiotech S.A., 28 avenue de Sévelin, 1004 Lausanne, Switzerland

Correspondence should be addressed to E. Chappel; moc.hcetoibed@leppahc.e

Received 1 March 2017; Accepted 10 May 2017; Published 31 May 2017

Academic Editor: Paolo Bruschi

Copyright © 2017 S. Fournier and E. Chappel. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A numerical model based on equivalent electrical networks has been built to simulate the dynamic behavior of a positive-displacement MEMS micropump dedicated to insulin delivery. This device comprises a reservoir in direct communication with the inlet check valve, a pumping membrane actuated by a piezo actuator, two integrated piezoresistive pressure sensors, an anti-free-flow check valve at the outlet, and finally a fluidic pathway up to the patient cannula. The pressure profiles delivered by the sensors are continuously analyzed during the therapy in order to detect failures like occlusion. The numerical modeling is a reliable way to better understand the behavior of the micropump in case of failure. The experimental pressure profiles measured during the actuation phase have been used to validate the numerical modeling. The effect of partial occlusion on the pressure profiles has been also simulated. Based on this analysis, a new management of partial occlusion for MEMS micropump is finally proposed.