Microfluidic Biosensor Based on Microwave Substrate-Integrated Waveguide Cavity Resonator

Figure 6

Simulated and measured return losses (on linear scale) of the proposed biosensor with (a) an empty microwell. (b) Simulated and measured return losses (on linear scale) with PBS solution and FB cells are compared while 3 μL fluid was injected in each case. The resonance frequency switched to 13.46 GHz and 13.48 GHz, respectively, when PBS solution and FB cells were injected in the microwell. (c) Zoom-in view of (b) to demonstrate the frequency shift and return loss modification after loading FB cells. The S11 (on a linear scale) changes from 0.356 to 0.3 when, respectively, PBS and FB cells are injected.

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(b)

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