Research Article

Reduced Graphene Oxide Decorated with AuNPs as a New Aptamer-Based Biosensor for the Detection of Androgen Receptor from Prostate Cells

Figure 2

(a) Cyclic voltammograms of GC electrode with AuNPs (black line) and AuNPs conjugated with graphene (red line) in 0.1 M PBS buffer (ph 7.4). (b) Cyclic voltammograms of GC-rGO-AuNPs electrode at different scan rates (A–I: 20, 30, 50, 60, 90, 100, 150, 200, and 250 mV/s) in 0.1 M PBS buffer (pH 7.4). (c) Plot of redox peaks current versus square root of scan rate, cathodic peak (black square), and anodic peak (red square). (d) Peak-to-peak separation as a function of the potential scan rate. (e) Impedance spectroscopy GC-rGO-AuNPs electrodes. Nyquist plots for PEG-Au electrodes containing bare GC electrode (black square), GC-rGO (red circle), GC-rGO-AuNPs (green triangle), MCH backfilling (blue triangle), and GC-rGO-AuNPs (pink diamond) in the presence of 50 ng/mL of recombinant protein. Frequency intervals were from 0.001 Hz to 10000.0 Hz.

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