Comparative Assessment of Affinity-Based Techniques for Oriented Antibody Immobilization towards Immunosensor Performance Optimization

Figure 1

Schematic representation of the random antibody immobilization on GOPTS-functionalized Si₃N₄ surfaces (a) and the two techniques followed to achieve the oriented immobilization of antibodies onto the surfaces: boronate ester chemistry (b) and protein A/G (c).

(a)

(b)

(c)