A Troubling Diagnosis of Verrucous Squamous Cell Carcinoma (“the Bad Kind” of Keratosis) and the Need of Clinical and Pathological Correlations: A Review of the Literature with a Case Report
Figure 1
Clinical findings and histopathological details. Clinical aspects at the first observation: a verrucous, exophytic mass, about 1 cm in diameter, localized in the hard palate (a) at the upper right premolars and extending to the vestibular side of the gingival (b). Clinical findings 15 days later: in two weeks the lesion grew larger and triplicated its size (c, d). Staining by toluidine blue and Lugol was performed to guide incisional biopsies (e, f). Histological details of an area with mild basal cytological atypia: vesicular nuclei with prominent eosinophilic nucleoli ((g, h); Haematoxylin and Eosin, 40). Superficial “church pinnacles” dyskeratosis ((i); Haematoxylin and Eosin, 10).
