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Journal of Skin Cancer
Volume 2011, Article ID 406859, 7 pages
http://dx.doi.org/10.1155/2011/406859
Case Report

Pigmented Nodular Basal Cell Carcinomas in Differential Diagnosis with Nodular Melanomas: Confocal Microscopy as a Reliable Tool for In Vivo Histologic Diagnosis

1Department of Dermatology and Venereology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
2Department of Pathology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy
3Department of Anatomy and Histology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41100 Modena, Italy

Received 29 June 2010; Accepted 23 September 2010

Academic Editor: Daniela Massi

Copyright © 2011 Alice Casari et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Nodular basal cell carcinoma, especially when pigmented, can be in differential diagnosis with nodular melanomas, clinically and dermoscopically. Reflectance confocal microscopy is a relatively new imaging technique that permits to evaluate in vivo skin tumors with a nearly histological resolution. Here, we present four cases of challenging nodular lesions where confocal microscopy was able to clarify the diagnosis.