Incidental Cutaneous Reaction Patterns: Epidermolytic Hyperkeratosis, Acantholytic Dyskeratosis, and Hailey-Hailey-Like Acantholysis: A Potential Marker of Premalignant Skin Change

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td align="left">Diagnosis</td><td align="left">Histology</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td align="left">Epidermolytic hyperkeratosis</td><td align="left">Perinuclear  vacuolization of keratinocytes in the upper epidermis, irregular keratohyaline granules, and compact hyperkeratosis</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Focal acantholytic dyskeratosis</td><td align="left">Acantholysis and dyskeratosis at all levels of the epidermis, suprabasalar clefting,  hyperkeratosis, and parakeratosis</td></tr><tr><td align="center" colspan="2"><hr/></td></tr><tr><td align="left">Hailey-Hailey-like acantholysis</td><td align="left">Prominent  acantholysis at all epidermal levels with epidermal hyperplasia and often suprabasal clefting</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Journal of Skin Cancer

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Table 1: Incidental Cutaneous Reaction Patterns: Epidermolytic Hyperkeratosis, Acantholytic Dyskeratosis, and Hailey-Hailey-Like Acantholysis: A Potential Marker of Premalignant Skin Change 

Table 1 | Incidental Cutaneous Reaction Patterns: Epidermolytic Hyperkeratosis, Acantholytic Dyskeratosis, and Hailey-Hailey-Like Acantholysis: A Potential Marker of Premalignant Skin Change 