Table 2: Summary of pERK and pS6 IHC staining in normal (noncancer), AK, BCC, and SCC skin samples.

P value*Total

pERK staining

Normal Skin024024
 AK0401.00004
 BCC1755<0.000127
 SCC01160.002817

pS6 staining

Normal Skin8008
 AK2020.09094
 BCC5416<0.000125
 SCC1213<0.000116

*Compared to normal skin by Fisher’s exact test. P values for overall comparison are shown. See text for a subset analysis.