Journal of Skin Cancer
Volume 2012, Article ID 404615, 5 pages
http://dx.doi.org/10.1155/2012/404615
Review Article
Melanoma in Organ Transplant Recipients: Incidence, Outcomes and Management Considerations
The Dermatology Centre and Manchester Academic Health Science Centre, University of Manchester and Salford Royal NHS Foundation Trust, Manchester M6 8HD, UK
Received 8 August 2012; Accepted 2 November 2012
Academic Editor: Giuseppe Argenziano
Copyright © 2012 Faisal R. Ali and John T. Lear. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Linked References
- S. Hariharan, C. P. Johnson, B. A. Bresnahan, S. E. Taranto, M. J. McIntosh, and D. Stablein, “Improved graft survival after renal transplantation in the United States, 1988 to 1996,” The New England Journal of Medicine, vol. 342, no. 9, pp. 605–612, 2000. View at Publisher · View at Google Scholar · View at Scopus
- S. Euvrard, J. Kanitakis, and A. Claudy, “Skin cancers after organ transplantation,” The New England Journal of Medicine, vol. 348, no. 17, pp. 1681–1691, 2003. View at Publisher · View at Google Scholar · View at Scopus
- E. A. Engels, R. M. Pfeiffer, J. F. Fraumeni Jr. et al., “Spectrum of cancer risk among US solid organ transplant recipients,” The Journal of the American Medical Association, vol. 306, no. 17, pp. 1891–1901, 2011. View at Google Scholar
- V. Madan, J. T. Lear, and R. M. Szeimies, “Non-melanoma skin cancer,” The Lancet, vol. 375, no. 9715, pp. 673–685, 2010. View at Publisher · View at Google Scholar · View at Scopus
- NICE, “Improving outcomes for patients with skin tumours including melanoma: the manual (2006 guidance),” National Institute of Clinical Excellence, 2006.
- M. H. Greene, T. I. Young, and W. H. Clark Jr., “Malignant melanoma in renal-transplant recipients,” The Lancet, vol. 1, no. 8231, pp. 1196–1199, 1981. View at Google Scholar · View at Scopus
- J. D. Brewer, L. J. Christenson, A. L. Weaver et al., “Malignant melanoma in solid transplant recipients: collection of database cases and comparison with surveillance, epidemiology, and end results data for outcome analysis,” Archives of Dermatology, vol. 147, no. 7, pp. 790–796, 2011. View at Google Scholar · View at Scopus
- R. N. Matin, D. Mesher, C. M. Proby et al., “Melanoma in organ transplant recipients: clinicopathological features and outcome in 100 cases,” American Journal of Transplantation, vol. 8, no. 9, pp. 1891–1900, 2008. View at Publisher · View at Google Scholar · View at Scopus
- I. Penn, “Malignant melanoma in organ allograft recipients,” Transplantation, vol. 61, no. 2, pp. 274–278, 1996. View at Publisher · View at Google Scholar · View at Scopus
- L. Le Mire, K. Hollowood, D. Gray, C. Bordea, and F. Wojnarowska, “Melanomas in renal transplant recipients,” British Journal of Dermatology, vol. 154, no. 3, pp. 472–477, 2006. View at Publisher · View at Google Scholar · View at Scopus
- J. N. Bouwes Bavinck, D. R. Hardie, A. Green et al., “The risk of skin cancer in renal transplant recipients in Queensland, Australia: a follow-up study,” Transplantation, vol. 61, no. 5, pp. 715–721, 1996. View at Publisher · View at Google Scholar · View at Scopus
- A. G. R. Sheil, “Cancer after transplantation,” World Journal of Surgery, vol. 10, no. 3, pp. 389–396, 1986. View at Google Scholar · View at Scopus
- B. Lindelöf, B. Sigurgeirsson, H. Gäbel, and R. S. Stern, “Incidence of skin cancer in 5356 patients following organ transplantation,” British Journal of Dermatology, vol. 143, no. 3, pp. 513–519, 2000. View at Publisher · View at Google Scholar · View at Scopus
- Q. Q. Dinh and A. H. Chong, “Melanoma in organ transplant recipients: the old enemy finds a new battleground,” Australasian Journal of Dermatology, vol. 48, no. 4, pp. 199–207, 2007. View at Publisher · View at Google Scholar · View at Scopus
- C. M. Vajdic, S. P. McDonald, M. R. E. McCredie et al., “Cancer incidence before and after kidney transplantation,” Journal of the American Medical Association, vol. 296, no. 23, pp. 2823–2831, 2006. View at Publisher · View at Google Scholar · View at Scopus
- I. Penn, “De novo malignances in pediatric organ transplant recipients,” Pediatric Transplantation, vol. 2, no. 1, pp. 56–63, 1998. View at Google Scholar · View at Scopus
- P. Jensen, S. Hansen, B. Moller et al., “Skin cancer in kidney and heart transplant recipients and different long-term immunosuppressive therapy regimens,” Journal of the American Academy of Dermatology, vol. 40, no. 2, part 1, pp. 177–186, 1999. View at Publisher · View at Google Scholar · View at Scopus
- J. M. Thomas, J. Newton-Bishop, R. A'Hern et al., “Excision margins in high-risk malignant melanoma,” The New England Journal of Medicine, vol. 350, no. 8, pp. 757–766, 2004. View at Publisher · View at Google Scholar · View at Scopus
- J. R. Marsden, J. A. Newton-Bishop, L. Burrows et al., “Revised UK guidelines for the management of cutaneous melanoma 2010,” Journal of Plastic, Reconstructive and Aesthetic Surgery, vol. 63, no. 9, pp. 1401–1419, 2010. View at Publisher · View at Google Scholar · View at Scopus
- C. C. Otley, D. Berg, C. Ulrich et al., “Reduction of immunosuppression for transplant-associated skin cancer: expert consensus survey,” British Journal of Dermatology, vol. 154, no. 3, pp. 395–400, 2006. View at Publisher · View at Google Scholar · View at Scopus
- F. O. Zwald, L. J. Christenson, E. M. Billingsley et al., “Melanoma in solid organ transplant recipients,” American Journal of Transplantation, vol. 10, no. 5, pp. 1297–1304, 2010. View at Publisher · View at Google Scholar · View at Scopus
- C. C. Otley, M. D. Griffin, M. R. Charlton, B. S. Edwards, M. Neuburg, and T. Stasko, “Reduction of immunosuppression for transplant-associated skin cancer: thresholds and risks,” British Journal of Dermatology, vol. 157, no. 6, pp. 1183–1188, 2007. View at Publisher · View at Google Scholar · View at Scopus
- S. Euvrard, E. Morelon, L. Rostaing et al., “Sirolimus and secondary skin-cancer prevention in kidney transplantation,” The New England Journal of Medicine, vol. 367, no. 4, pp. 329–339, 2012. View at Google Scholar
- G. E. Koehl, J. Andrassy, M. A. Guba et al., “Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice,” Transplantation, vol. 77, no. 9, pp. 1319–1326, 2004. View at Publisher · View at Google Scholar · View at Scopus
- D. C. Strauss and J. M. Thomas, “Transmission of donor melanoma by organ transplantation,” The Lancet Oncology, vol. 11, no. 8, pp. 790–796, 2010. View at Publisher · View at Google Scholar · View at Scopus
- K. L. Lentine, A. Vijayan, H. Xiao et al., “Cancer diagnoses after living kidney donation: linking U.S. registry data and administrative claims,” Transplantation, vol. 94, no. 2, pp. 139–144, 2012. View at Google Scholar
- E. F. Scanlon, R. A. Hawkins, W. W. Fox, and W. S. Smith, “Fatal homotransplanted melanoma: a case report,” Cancer, vol. 18, pp. 782–789, 1965. View at Google Scholar · View at Scopus
- D. Jeremy, R. H. Farnsworth, M. R. Robertson, D. L. Annetts, and G. F. Murnaghan, “Transplantation of malignant melanoma with cadaver kidney,” Transplantation, vol. 13, no. 6, pp. 619–620, 1972. View at Google Scholar · View at Scopus
- M. S. Peters and I. D. Stuard, “Metastatic malignant melanoma transplanted via a renal homograft. A case report,” Cancer, vol. 41, no. 6, pp. 2426–2430, 1978. View at Google Scholar · View at Scopus
- R. M. Fairman, R. A. Grossman, C. F. Barker, and L. J. Perloff, “Inadvertent transplantation of a melanoma,” Transplantation, vol. 30, no. 5, pp. 328–330, 1980. View at Google Scholar · View at Scopus
- L. J. Wilson, R. T. Horvat, L. Tilzer, A. M. Meis, L. Montag, and M. Huntrakoon, “Identification of donor melanoma in a renal transplant recipient,” Diagnostic Molecular Pathology B, vol. 1, no. 4, pp. 266–271, 1992. View at Google Scholar · View at Scopus
- G. J. Elder, P. Hersey, and P. Branley, “Remission of transplanted melanoma—clinical course and tumour cell characterisation,” Clinical Transplantation, vol. 11, no. 6, pp. 565–568, 1997. View at Google Scholar · View at Scopus
- M. G. Suranyi, P. G. Hogan, M. C. Falkk et al., “Advanced donor origin melanoma in a renal transplant recipient: immunotherapy, cure, and retransplantation,” Transplantation, vol. 66, no. 5, pp. 655–661, 1998. View at Publisher · View at Google Scholar · View at Scopus
- J. K. Stephens, G. T. Everson, C. L. Elliott et al., “Fatal transfer of malignant melanoma from multiorgan donor to four allograft recipients,” Transplantation, vol. 70, no. 1, pp. 232–236, 2000. View at Google Scholar · View at Scopus
- R. M. MacKie, R. Reid, and B. Junor, “Fatal melanoma transferred in a donated kidney 16 years after melanoma surgery,” The New England Journal of Medicine, vol. 348, no. 6, pp. 567–568, 2003. View at Publisher · View at Google Scholar · View at Scopus
- G. Morris-Stiff, A. Steel, P. Savage et al., “Transmission of donor melanoma to multiple organ transplant recipients,” American Journal of Transplantation, vol. 4, no. 3, pp. 444–446, 2004. View at Publisher · View at Google Scholar · View at Scopus
- G. Zavos, I. Papaconstantinou, C. Chrisostomidis, and A. Kostakis, “Metastatic melanoma within a transplanted kidney: a case report,” Transplantation Proceedings, vol. 36, no. 5, pp. 1411–1412, 2004. View at Publisher · View at Google Scholar · View at Scopus
- C. A. Milton, J. Barbara, J. Cooper, M. Rao, C. Russell, and G. Russ, “The transmission of donor-derived malignant melanoma to a renal allograft recipient,” Clinical Transplantation, vol. 20, no. 5, pp. 547–550, 2006. View at Publisher · View at Google Scholar · View at Scopus
- M. Cankovic, M. D. Linden, and R. J. Zarbo, “Use of microsatellite analysis in detection of tumor lineage as a cause of death in a liver transplant patient,” Archives of Pathology and Laboratory Medicine, vol. 130, no. 4, pp. 529–532, 2006. View at Google Scholar · View at Scopus
- A. W. Loren, S. Desai, R. C. Gorman, and L. M. Schuchter, “Retransplantation of a cardiac allograft inadvertently harvested from a donor with metastatic melanoma,” Transplantation, vol. 76, no. 4, pp. 741–743, 2003. View at Publisher · View at Google Scholar · View at Scopus
- H. Tsao, A. B. Cosimi, and A. J. Sober, “Ultra-late recurrence (15 years or longer) of cutaneous melanoma,” Cancer, vol. 79, no. 12, pp. 2361–2370, 1997. View at Google Scholar
- J. F. Buell, T. M. Beebe, J. Trofe et al., “Donor transmitted malignancies,” Annals of Transplantation, vol. 9, no. 1, pp. 53–56, 2004. View at Google Scholar · View at Scopus
- N. S. Bajaj, C. Watt, D. Hadjiliadis et al., “Donor transmission of malignant melanoma in a lung transplant recipient 32 years after curative resection,” Transplant International, vol. 23, no. 7, pp. e26–e31, 2010. View at Publisher · View at Google Scholar · View at Scopus