Germ Cell Proteins in Melanoma: Prognosis, Diagnosis, Treatment, and Theories on Expression

Table 1

CTA diagnostic potential.

	% MM positive	% BN positive	% NS positive	Reference
3 CTAs	50	0		[14]
6 CTAs	77	0		[14]
SPANX	80.9	25	0	[17]
PRAME	88		0	[19, 20]
MAGE*		49		[16]

MM: melanoma; BN: benign nevi; NS: normal skin % of samples positive for expression of gene.
3 CTAs tested MAGE-A1, MAGE-A4, and NY-ESO-1.
6 CTAs tested MAGE-A1, MAGE-A4, NY-ESO-1, MAGE-C1, MAGE-A3, and GAGE.
∗Anti-MAGE antibody 57B.